Wolverhampton Wanderers stun Liverpool 2-1 with a 94th-minute winner to revive survival hopes and dent the Reds' top-five push, while Everton and Sunderland claim crucial Premier League victories.
Champions Manchester City struggled in this campaign and sit sixth in the table after winning only two of their last 10 league matches.
France forward Hugo Ekitike suffered a ruptured Achilles during Liverpool's Champions League clash against Paris St Germain on Tuesday.
Manchester City were drawn against Real Madrid in the Champions League knockout phase for the sixth time since the 2019-20 season after the draw for the last 16, quarterfinals and semifinals was made on Friday.
Everton have filed an appeal against their 10-point deduction by the Premier League, the club said on Friday.
Man City snatch chaotic 2-1 win at Liverpool to stay on Arsenal's heels
Manchester City and Arsenal face off in a crucial Premier League clash, with the title race hanging in the balance as City look to seize momentum.
Pep Guardiola remains optimistic about Manchester City's future despite their Champions League elimination by Real Madrid, highlighting the team's spirit and the importance of experience for new players.
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Arsenal took a seven-point lead at the top of the Premier League after a scoreless draw with Nottingham Forest on Saturday.
Manchester City captain Bernardo Silva will leave the club at the end of the season, assistant manager Pep Lijnders confirmed. The Portugal international's contract expires after a successful nine-year spell.
Images from the EPL matches played on Saturday.
Mario Lemina's early diving header handed Galatasaray a 1-0 victory over Liverpool in their Champions League last-16 first leg on Tuesday.
Liverpool manager Arne Slot must find a way to arrest the team's slide even as the pressure mounts on him, former skipper Steven Gerrard said.
Arsenal resume their Premier League title push with a nine-point lead after a morale-boosting win in Europe, but a resurgent Manchester City and an intense race for Champions League spots ensure a thrilling run-in.
Barcelona prepares to face Newcastle in the Champions League round of 16, with coach Hansi Flick emphasising the importance of the match. The team aims to improve on last season's semi-final exit and secure their first Champions League title since 2015.
Liverpool secured a dominant win over West Ham, while other Premier League matches saw Brentford edge Burnley in a seven-goal thriller and Everton secure a late victory against Newcastle.
'If we play at the level of Liverpool or Tottenham we'll do it again.'
Manchester City scored three goals in 17 second-half minutes and move within six points of league leaders Arsenal.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
Liverpool striker Alexander Isak is expected to be sidelined for at least a couple of months after breaking his leg and undergoing surgery.
Manchester City's title hopes take a hit after a dramatic 3-3 draw with Everton, with Jeremy Doku's late goal rescuing a point as Arsenal maintain the advantage.
Arsenal missed the chance to go eight points clear at the top of the Premier League in a turgid 0-0 draw with champions Liverpool.
Southampton secured a 1-0 victory against Fulham with a late penalty, making them the first non-Premier League club to reach the FA Cup quarter-finals this season.
European champions Liverpool made an emphatic start to the new Premier League season by scoring three times in the opening half an hour as they taught promoted Norwich City a harsh lesson with a 4-1 thrashing at Anfield on Friday.
Liverpool forward Mohamed Salah is destroying his legacy at the club with his fiery reaction to being left out of the side, former Manchester United striker Wayne Rooney said.
Matheus Cunha struck just before half-time to earn Manchester United a 1-0 victory at luckless Chelsea on Saturday, taking them a big step closer to Champions League football next season.
Liverpool's 30-year English title drought ended on Thursday as they were confirmed as English Premier League champions courtesy of second-placed Manchester City's 2-1 loss at Chelsea. A superb solo goal by Christian Pulisic and a Willian penalty gave Chelsea a 2-1 win over Manchester City at Stamford Bridge, a result that handed Liverpool the Premier League title.
Second-placed City would have reduced Arsenal's advantage to two points but instead were frustrated as their winning streak in all competitions was halted at eight.
Goals from Pedro Neto and Enzo Fernandez earned Chelsea a 2-0 victory at lowly Burnley on Saturday, a win that moved the Blues within three points of Premier League leaders Arsenal.
Nigerian international Odion Ighalo scored twice as a buoyant Watford won 3-0 at home to Liverpool to consolidate seventh position in the Premier League, only one point behind the top four.
Two Steven Gerrard penalties helped Liverpool to a crushing 3-0 victory at bitter rivals Manchester United on Sunday to leave them breathing down the necks of Premier League leaders Chelsea.
Man City ease to 3-0 win over Liverpool as Guardiola celebrates 1,000th game in style
'Project Big Picture' called for the biggest six clubs in the Premier League, along with three other long-term members, to be given 'special voting rights' that would effectively put them in command of the world's most commercially successful league -- and leave the rest as second-class passengers.
Brief reports of Premier League matches on Saturday.
Liverpool will cover most miles of any Premier League club in pre-season preparation.
'We wouldn't have taken the first step to get back to training if we weren't convinced we had created a very safe environment for our players'
Upcoming matches in the English Premier League.
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